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| April 22nd, 2006 | Event | 243 people are injured in pro-democracy protest in Nepal after Nepali security forces open fire on protesters against King Gyanendra. |
| April 22nd, 2006 | Event | Four Canadian soldiers are killed 75 kilometers north of Kandahar, Afghanistan by a roadside bomb planted by Taliban militants, the worst single day combat loss for the Canadian army since the Korean War. |
| April 22nd, 2004 | Event | Two fuel trains collide in Ryongchon, North Korea, killing up to 150 people. |
| April 22nd, 2000 | Event | In a pre-dawn raid, federal agents seize six-year-old Elian Gonzalez from his relatives home in Miami, Florida. |
| April 22nd, 2000 | Event | The Big Number Change takes place in the United Kingdom. |
| April 22nd, 1998 | Event | Disney s Animal Kingdom opens at Walt Disney World near Orlando, Florida, United States. |
| April 22nd, 1997 | Event | Haouch Khemisti massacre in Algeria93 villagers killed. |
| April 22nd, 1997 | Event | The Japanese embassy hostage crisis ends in Lima, Peru. |
| April 22nd, 1993 | Event | The Holocaust Memorial Museum in Washington, DC is dedicated. |
| April 22nd, 1993 | Event | The web browser Mosaic version 1.0 is released. |
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